MJBizCon, the world’s largest and most influential B2B cannabis Conference and Expo, has announced Grammy-nominated artist and Khalifa Kush Co-Founder, Wiz Khalifa, as keynote speaker and concert headliner on Wednesday, December 2, at the Las Vegas Convention Center.

Long before legalization went mainstream, Wiz Khalifa made cannabis part of his identity, his music, and his message. Since the 2010s, he’s turned that passion into a premium cannabis business, Khalifa Kush, built on the culture he helped shape.

Khalifa will share his journey from artist to cannabis entrepreneur during From Mixtapes to Market Share: Wiz Khalifa’s Cannabis Playbook, a 30-minute fireside chat taking place Wednesday, December 2, at 1:00 p.m. on the General Session Stage (N109). The keynote is open to all MJBizCon attendees, regardless of badge type.

The conversation will explore how Khalifa transformed a personal strain into a recognized consumer brand while maintaining the cultural authenticity that helped establish it. He’ll discuss the importance of choosing the right partners across cultivation, distribution, and retail, the challenges of scaling a cannabis business, and his perspective on where the global cannabis market is headed.

Later that day, Khalifa will trade the keynote stage for the music stage, delivering a live performance at 5:00 p.m. at The Gas Station, MJBizCon’s all-new live music stage powered by Weedmaps.

Debuting at MJBizCon 2026, The Gas Station brings live music and entertainment directly to the Expo Floor, giving attendees a new way to close out the show day before heading into the Las Vegas nightlife. Khalifa will headline Wednesday’s performances alongside an opening act to be announced. Live music will continue Thursday, December 3, with additional artists and performances to be revealed.

MJBizCon 2026 takes place December 1–4 at the Las Vegas Convention Center, beginning with Pre-Conference Certifications and special programming on Tuesday, December 1.